Diabetes in Developing Countries

Diabetes in developing countries Deaths from diabetes, which has two primary forms including type1 and type2 diabetes, have become a significant problem in the world. Nowadays, diabetes is still a disease not having precise method to cure. As a result of surplus blood sugar, it has a negative effect on the human body and leads to several complications, such as vision problems, kidney damage, nerve damage and heart and circulation problems (Pollock, 2006). Consequently, the increased risk of these diseases makes it become one of the major causes of deaths.
For example, according to the WHO (2011), more than 346 million people were diagnosed with it worldwide and between 50% and 80% of them died from CVD. With the development of health care, the mortality in developed countries was decrease, while the situation in developing countries is so serious that 80% of diabetes deaths exist in low and middle income countries (WHO, 2011). For instance, such countries in The Middle East, Pacific Islands and Southeast Asia had 115million diabetic patients in 2000 and the WHO (2011) predicts that the number will double between 2005 and 2030.
To mitigate the effects of diabetes, the causes of it need to be detected. Type 1 diabetes, which is known by lacking insulin production, results from several causes and possible factors. First, genes attribute mainly to it. More than 18 genetic locations related to it have been discovered by researchers and they have found that people with an especially HLA complex which means human leukocyte antigen, are more likely to develop it. A good illustration of it is other autoimmune disorders may caused by such complexes, such as rheumatoid arthritis, ankylosing spondylitis, or juvenile rheumatoid arthritis (Smith, 2010).

The second factor is a viral infection which may affects the disease by attacking immune system. For instance, Kamiah (2010) states that a series of diseases from gastrointestinal problems to myocarditis can created by the coxsackie B virus. In addition, there are some special conditions which may attribute to it. For example, certain drugs including corticosteroids, beta blockers, and phenytoin, rare genetic disorders such as Klinefelter syndrome and Wolfram syndrome, and hormonal disorders such as acromegaly and hyperthyroidism all raise the possibility of it (Simon, 2009).
It has been one of the most increased diseases worldwide, however, type 2 diabetes is more common. Unlike type 1 diabetes, causes of type 2 diabetes, which results from the ineffective use of insulin (WHO,2011), usually are multifactorial. First, being overweight or obese is a primary reason for it. The increased risk of it may bring several complications including heart disease, stroke and some cancers. A good illustration of this is 82% of people with it are caused by overweight or obese and such complications (Vann,2009).
The second is genetic factors which have been found more than 10 genic material associated with it. For example, there are more possibilities for people to get it if they have close relatives having it, such as parents and siblings. Thirdly, ethnic origin also plays a part in it. For instance, NHS (2010) points out that people with it from South Asian, African, and Middle Eastern are six times likely than people in the UK. In addition, incorrect living styles such as poor eating habits, too much TV time and physical inactivity also have a negative effect on it.
It is often not a single factor but two or more causes above combined to lead to it. According to the CDC (2010), such combinations give rise to approximately 95% of it in the U. S. As can be seen from data, diabetes in developing countries has become a huge problem and the mortality from it has a continued increase worldwide. Not only government, but people should change their attitudes and aware the importance in order to prevent it.